Colorescience has published a study in the Journal of Cosmetic Dermatology using an open-label assessment of the efficacy and tolerability of a skin care regimen, Colorescience All Calm Sensitive Skin, for treating subjects with visible and physical symptoms of sensitive skin.
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The 12-week clinical trial examined subjects with facial redness and sensitive skin, who were divided into two groups. Group A had not used any professional-grade topical skin care, office-based treatments or prescription products to address their sensitive skin. Group B subjects were actively receiving treatment using professional topical skin care or prescription products.
According to the authors, this is a significant study design because it represents the two types of patients who are seeking to address facial redness and sensitive skin. The results of the study showed the mean Overall Redness Scale Score improved by 25% at week 12 with results seen as early as two months.
At the end of the study, more than 50% of subjects experienced marked global improvement. At week 12, all subjects agreed or strongly agreed that their facial redness was less noticeable; skin appeared less inflamed; overall skin appearance improved; and skin looked and felt healthier. Additionally, 100% of subjects reported that they would continue to use the regimen.
The All Calm Sensitive Skin Regimen products address environmental triggers to help calm and soothe sensitive, easily irritated skin, hydrate, support skin barrier health, smooth skin texture, and provide immediate correction and ongoing relief of redness.
According the the company, the findings indicated the products were well-tolerated and improved the visible and physical symptoms of sensitive skin. Importantly, the treatment also helped to restore the confidence of the participants.
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“Having a non-steroidal topical solution to address sensitive skin concerns is important to me and my patients," said Ellen O. Turner, M.D., board-certified dermatologist at the Dermatology Office of Dr. Ellen Turner. "As the lead investigator for this study, I was able to evaluate and observe the impressive results from the All Calm Sensitive Skin Regimen. I am thrilled to offer these safe and effective products to my patients.”
Following is the ingredient disclosure for one product from the regimen.
Ingredients (All Calm Clinical Redness Corrector SPF 50): Active Ingredients: Titanium Dioxide 11.6%, Zinc Oxide 8.6%. Inactive Ingredients: Cyclopentasiloxane, Caprylic/Capric Triglyceride, Dimethicone Crosspolymer, Water/Aqua/Eau, Niacinamide, Dimethicone/Vinyl Dimethicone Crosspolymer, Disteardimonium Hectorite, Propylene Carbonate, Disodium Lauriminodipropionate Tocopheryl Phosphates, Crithmum Maritimum Extract, Magnolia Officinalis Bark Extract, Zingiber Officinale (Ginger) Root Extract, Magnesium Carboxymethyl Beta-Glucan, Jojoba Esters, Bisabolol, Silica, Polyhydroxystearic Acid, Dimethiconol, Alumina, Glyceryl Behenate/Eicosadioate, Phenoxyethanol, Triethoxycaprylylsilane, Ethylhexylglycerin, Tocopherol, Dehydroacetic Acid, Benzoic Acid, Glycolic Acid, Chloroacetic Acid, Chromium Oxide Greens (CI 77288), Iron Oxides (CI 77491, CI 77492, CI 77499).