
PALO ALTO, Calif., -- Midi Health, a women's telehealth company, announced its prescription skincare line. The line is built to address the hormonal changes in women's skin, beginning in their 30's that accelerates through menopause.
Hormonal shifts in midlife can lead to dryness, thinning, adult acne and accelerated skin damage. Midi's prescription skincare line is formulated by menopause specialists, board-certified physicians, scientists and pharmacists. The line includes the Estriol+ Face Cream, Estriol+ Eye Cream, Hydroquinone Even Tone Cream, Copper Peptide Repair Cream and the Tretinoin Active Renewal Cream.
With the line, Midi aims to target the root causes of midlife skin issues, including collagen loss, slowing cell renewal, barrier dysfunction and hyperpigmentation.
"We're building the definitive care platform for women's health from the first signs of hormone change through every transition that follows," said Joanna Strober, chief executive officer and co-founder of Midi Health. "Skin is a direct reflection of that hormone story, and for too long, women have been given cosmetic answers to a clinical question. Just like everything else we do at Midi, this skincare line was born from listening to our patients and acting on what they need. They were asking for solutions, and because our clinicians are already treating the hormones driving these changes, now they can treat the skin, too."
"Women lose about 1% of their collagen annually throughout adulthood, and this loss accelerates dramatically during menopause," said Dr. Kathleen Jordan, chief medical officer of Midi Health. "These biological changes mean women have to navigate dryness, melasma, dullness, sagging, uneven texture, and fine lines. Midi's skincare formulations were created by women's health experts who deeply understand how shifting levels of estrogen, progesterone, and other hormones during midlife can cause skin to change."
The Copper Peptide Repair Cream is the newest in the product line. The cream can work in alignment with the body's biology and calm irritability and restore natural repair processes. Beginning in their 20's, women might experience declining levels of their native peptide GHK-Cu. This decline can slow the skin's ability to repair itself, leaving it potentially vulnerable to environmental damage, barrier breakdown and inflammation.
Each product in the Midi skincare line is effective on its own. Midi clinicians curated targeted combinations to address a mix of hormone-driven skin changes they see most often in Midi's patients.
"Skin has estrogen receptors throughout its layers, which means when estrogen levels begin to decline, the effects show up directly in the skin. This can result in reduced collagen synthesis, impaired barrier function, decreased sebum production, and slower cell turnover. Progesterone plays a role too, influencing sebaceous gland activity and skin thickness. At Midi, our clinicians are already treating the hormonal shifts driving these changes systemically, and now our skincare line allows us to address those same mechanisms at the skin level," said Dr. Ava Mainieri, PhD, Vice President of Clinical Operations at Midi Health.








