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Is an Acne Vaccine in Our Future?

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A group of researchers have taken steps toward developing and creating a vaccine for acne, and they published their findings in the Journal of Investigative Dermatology. In their research, the investigators discover how a mutation of the Christie-Atkins-Munch-Petersen (CAMP) factor, a toxin secreted from the of Propionibacterium acnes (P. acnes) bacteria, can diminish P. acnes colonization and inflammation in mice.

The researchers then sought to see if could inhibit inflammation through the use of antibodies; they found that the application of monoclonal antibodies to CAMP 2 factor did decrease an inflammatory response in mice and ex vivo in human skin cells from collected acne lesions. 

"Once validated by a large-scale clinical trial, the potential impact of our findings is huge for the hundreds of millions of individuals suffering from acne vulgaris," explained lead investigator Chun-Ming Huang, Ph.D., Department of Dermatology, University of California, San Diego.

While acne may not be a life-threatening disease, it does impact countless people worldwide, and it has an emotional impact on a person's self-esteem.

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