Researchers have developed an allergen-depleted and anti-inflammatory fragrance that can be used in moisturizers for people with extremely dry, xerotic skin, per EurekAlert.
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This news comes from Beiersdorf researchers in Germany who reported the results at the 29th EADV Congress, EADV Virtual, showing two tests that prove the fragrance is anti-inflammatory.
Tests on skin cells found that the anti-inflammatory ingredients of the allergen-depleted fragrance composition reduced expression of both Prostaglandin E2 and Interleukin-8 after applying a stressor substance.
The researchers also studied the fragrance formulated in a moisturizer which was applied to volunteers after they shaved their skin on three consecutive days to induce skin irritation.They found that skin redness was significantly reduced in the skin treated with the moisturizer.
The fragrance was developed without 26 commonly known allergens as well as without the additional 60+ potential allergens currently under evaluation. The fragrance still has a pleasant scent, which can improve the cosmetic acceptability of moisturizers and enhance patients' treatment adherence.
The study shows among 86 people with dry skin who used the fragrance moisturizer for two weeks, 97% agree they enjoy applying it. While 91% confirmed that the scented lotion makes their care routine more pleasant and 71% confirmed that they like the scented product better than the unscented moisturizer they normally use.
Julia Gallinger Ph.D., a senior scientist at Beiersdorf AG's Research and Development department said, "A moisturizer containing our novel fragrance could provide an improved treatment option for people with dry skin conditions. It would be both pleasant to use due to its scent, enhancing patients` treatment adherence, and actively soothe inflammation. Hence, the long-standing paradigm of fragrance moisturizers considered as allergenic risk in the treatment of xerotic dermatoses may soon become obsolete. The fragrance has been integrated into two new Eucerin UreaRepair PLUS products for dry skin to provide skin care with a pleasurable experience."
