The XERF system combines 6.78 MHz and 2 MHz RF energy to target multiple skin depths, including heating fibrous septa.
Courtesy of Prostock-studio at Adobe Stock
Energy-based device company, Cynosure Lutronic, received clearance for its XERF system, a radiofrequency technology for face and neck skin tightening, in August 2025. The XERF system provides multi-frequency monopolar RF treatment and is starting to see itself rolled out in U.S. practices.
Log in to view the full article
Energy-based device company, Cynosure Lutronic, received clearance for its XERF system, a radiofrequency technology for face and neck skin tightening, in August 2025. The XERF system provides multi-frequency monopolar RF treatment and is starting to see itself rolled out in U.S. practices.
Predominantly manufacturing lasers and RF devices, this device was created by Cynosure Lutronic to tighten skin without the need for numbing, needles or downtime, meant for all skin types, per an Aug. 18 press release. Since this is a monopolar RF treatment, the device combines 6.78 MHz and 2 MHz frequencies, enabling providers to deliver energy at multiple tissue depths, including to heat the fibrous septa for reportedly lasting tightening effects.
Per the company, the 6.78 MHz frequency reaches the more surface level layers, while 2 MHz penetrates deeper into subcutaneous and adipose layers. Together, they remodel the structure of tissue to restore firmness subdermally through collagen and elastin thickening, strengthening and shortening.
Cynosure Lutronic's new XERF system received FDA clearance in August 2025, offering needle-free, no-downtime skin tightening using monopolar radiofrequency technology.Courtesy of Cynosure Lutronic
Cooling technology is also built into the device to follow the effects of these frequencies. Wave Fit Pulse and Integrated Cryogen Delivery work in tandem to regulate energy delivery while the skin is being tightened and to maintain surface temperature for a comfortable treatment, enforcing the fact that it doesn't require numbing to deliver.
According to Cynosure Lutronic, this technology optimizes energy and cooling delivery to protect the epidermis, facilitating deep dermal energy delivery while aiding patient comfort.
The tip delivering these dual frequencies is designed with a 3-way split spider pattern. This style was intended to reduce skin edge effects and ensure uniform energy delivery. “The XERF system incorporates the newest technology to safely deliver energy deeper down in the skin, while offering intelligent cooling for superior protection and patient comfort,” said Jordan V. Wang, MD, medical director of Laser & Skin Surgery Center in Pennsylvania.
