Physiology Sponsored by
High molecular weight hyaluronan from oral supplements does reach skin and joint tissues, supporting a role for the compound in such products, says a new study. “This report presents the first evidence for uptake and distribution to connective tissues of orally administered, high-molecular weight HA (hyaluronan),” wrote the researchers in the Journal of Agricultural and Food Chemistry.
The international team of researchers report that, despite widespread use of the ingredient in dietary supplements, no report in the literature previously existed confirming that oral HA intake leads to absorption or uptake.
HA is similar to the synovial fluid that surrounds your joints and acts as a lubricant and shock absorber. It is typically injected into the joints but has become popular as a nutraceutical competing with the likes of chondroitin sulphate and glucosamine as non-pharmaceutical or surgical means to deal with joint discomfort. HA is also increasingly being used as a cosmeceutical ingredient with some reports that it may deliver skin benefits.
The new study used Fenchem Biotek’s HyaMax HA ingredient. The Chinese company claims to hold 40% of the U.S. HA market, with the overall market reportedly growing at 15%.