The REVEAL (Randomized Controlled EValuation of Adalimumab Every Other Week Dosing in Moderate to Severe Psoriasis TriAL) included 1,200 patients. After 16 weeks, 71 percent of the patients who took the drug showed a 75 percent improvement in skin clearance, compared to 6.5 percent of patients who received a placebo.
Upper respiratory tract infection, headache and nasopharyngitis were the most common side effects reported by patients in the study.
Psoriasis is an autoimmune disease that causes raised, inflamed, scaly, red skin lesions that can crack and bleed. There is no cure for psoriasis, which affects about 125 million people worldwide. Of those, about 25 percent have moderate to severe psoriasis. The disease can occur at any age but typically appears between the ages of 15 and 35.