Sign in

DNA Repair Mechanisms and the Skin

Michael Q. Pugliese and Peter T. Pugliese, MD August 2014 issue of Skin Inc. magazine
Basal cell carcinoma

Basal cell carcinoma

Get the Skinny! This is just part of the article. Want the complete story, plus a host of other cutting-edge articles to make your job easier? Sign up!

Silently and efficiently, the cells of the skin work furiously to repair the damage that is incessantly assaulting your deoxyribose nucleic acid (DNA). Without these repair mechanisms, life would be impossible.

The major manifestation of DNA damage on the skin is skin cancer. Clients who have red hair and are Fitzpatrick Type I are the most susceptible to this type of damage, but anyone who is exposed to high levels of sun exposure is a candidate for DNA damage. If serious, most DNA damage to the skin will manifest as some type of lesion. If skin care professionals notice actinic keratosis, multiple ugly, pigmented spots or any lesion that cannot be recognized, they should immediately refer the client to a dermatologist.

In this article, only the basic mechanisms of DNA repair will be covered for the skin care professional by answering four essential questions.

  1. How does the skin become damaged?
  2. What type of damage is incurred by DNA and other organelles in the skin?
  3. How does the skin repair this damage?
  4. What can be used topically to assist in DNA repair?

Want the rest of the story? Simply sign up. It’s easy. Plus, it only takes 1 minute and it’s free!

Related Content



Welcome to the new!

Delivering the best information on the spa, skin care and wellness industry is our passion, and we’ve worked hard to design a powerful new website that incorporates cutting-edge technology to bring you:

  • Mobile-friendly Design
  • Integrated Sample Request
  • Refreshed Look and Feel
  • Dynamic Content
  • Free Registration

Mobile-friendly Design

Providing a unified experience from mobile to desktop, responsive design allows you to access Skin Inc. content from any device, whether you’re in the treatment room, at home or on the go!

Integrated Sample Request

Visit Featured Product pages to quickly and easily identify new suppliers and request product samples and information.

Dynamic Content

Articles are now linked with relevant products so you can find the products and treatments you need to provide the best results for your clients.

Free Registration

Create your user account to gain unlimited access to Skin Inc.’s unparalleled content.

Enjoy the New!

Thank you for joining the Skin Inc. community of passionate skin care professionals. We look forward to providing you the best information to enhance your career!