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Industry Speaks Out on Study Linking Moisturizer and Cancer in Mice

Posted: January 23, 2009

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According to Ellefson these suggestions have “inflicted unjustifiable damage to the reputations of the tested moisturizers, according to many commentaries in the lay press and correspondence to the manufacturers”. However, Lu and the team point out that their original article is conservative about the relevance of the work to humans and they cannot be held responsible for the interpretations of their work by others. A number of other industry experts have also commented on the study with some agreeing that further tests are necessary in order to investigate the human relevance of the work.

Brian Diffey, emeritus professor of photobiology at Newcastle University, agrees that the UVB-pretreatment of the mice is a poor surrogate for human sun exposure. However, he states that further work is needed to evaluate the risk, as opposed to the hazard, of the creams to humans. But, Professor Jonathan Rees from the University of Edinburgh warns that mice and humans are not very similar when it comes to skin cancer and questions the clinical relevance of the study.

Source: Journal of Investigative Dermatology, 2009, Volume 129, “Tumorigenic Effect of Some Commonly Used Moisturizing Creams when Applied Topically to UVB-Pretreated High-Risk Mice,’ Yao-Ping Lu, You-Rong Lou, Jian-Guo Xie, Qingyun Peng, Weiching J. Shih, Yon Lin and Allan H. Conney.

Comments and responses also published in Volume 129 of the Journal of Investigative Dermatology., January 21, 2009