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Hormones May Hold Clues to Healthy Aging

Posted: June 22, 2006
Specific hormones may play a key role in longevity and healthy aging, two new studies suggest.

Researchers found one hormone, adiponectin, at higher-than-average concentrations in 100-year-old women, while another study found that stimulating the body's production of growth hormone brought a youthful pep back to people in their 60s to 80s.

Both studies were presented Wednesday at the 6th International Congress of Neuroendocrinology, in Pittsburgh.

In the first study, Dr. Agnieszka Baranowska-Bik and colleagues from the University of Poland studied 133 women from 20 to 102 years of age, including 25 women who were 100 to 102 years old. The researchers were particularly interested in the women's levels of adiponectin.

Adiponectin is made by fat tissue and may be an important determinant of longevity. It is a peptide protein with anti-inflammatory properties that helps keep blood vessels clear of fatty deposits. Adinopectin also plays an important role in metabolism, particularly in the regulation of cholesterol and sugar.