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Bio-identical Hormone Replacement Therapy

By: Harvey S. Bartnof, MD
Posted: June 9, 2008, from the December 2006 issue of Skin Inc. magazine.

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Skin wrinkling in women is partially due to a decline in hormones—particularly estrogen and somatotropin, which is a growth hormone. HRT decreases skin wrinkling and sagging by naturally increasing hydration and oil secretion, as well as stimulating collagen. Growth HRT in women and men decreases skin wrinkling and sagging by naturally increasing hydration, collagen and skin thickness.

Growth hormone is commonly misunderstood. Just as female menopause—a decline in female-related hormones—exists, somatopause—a decline in growth hormone—also exists. It is listed in more than 50 references in the National Library of Medicine. Somatopause is a form of growth hormone deficiency. It leads to a reduction in muscle mass, an increase in fat mass, a loss of total body water—which is a cofactor for skin wrinkling—and a decline in energy, and it represents a cofactor for abnormal sleep. Growth HRT can be accomplished successfully in the vast majority of people who have this deficiency, but ongoing monitoring is required.

Refer your clients

If your clients are suffering from troublesome menopausal symptoms, refer them to a physician who can explain the best treatment options, and encourage them to inquire about BHRT. This natural alternative to chemical treatments may be just what the doctor ordered.


1AR Genazzani, Hormone Replacement Therapy and The Brain, Taylor & Francis (2003)

2HS Kupperman, Contemporary therapy of the menopausal syndrome. Journal of the American Medical Association 171, 1627-1637 (1959)