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The Biology Behind Eczema and Psoriasis
By: Claudia C. Aguirre, PhD
Posted: June 29, 2012, from the July 2012 issue of Skin Inc. magazine.
Erythrodermic psoriasis is a particularly inflammatory form of psoriasis that affects most of the body surface.
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3. AM Bowcock and W Cookson, The genetics of psoriasis, psoriatic arthritis and atopic dermatitis, Human Molecular Genetics 13 R43–R55 (2004)
4. FJ Smith, et al, Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris, Nat Genet 38 337–342 (2006)
5. CN Palmer, et al, Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis, Nat Genet 38 441–446 (2006)
6. SJ Brown, et al, Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy, J Allergy Clin Immunol 127 661–667 (2011)
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