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The Other Cause of Wrinkles: Sugar

Posted: July 30, 2013
Sugar causes wrinkles

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If that wasn't bad enough, grilling, frying, toasting and roasting foods all produce high levels of advanced glycation end products (AGEs). So things like crusted breads, grilled chicken, coffee (the beans are roasted!), and even granola—a health-nut staple—is an AGE double whammy, since it has lots of sugar and it's toasted. "When you're younger," explains SanMedica International's Amy Heaton, MD, PhD, "your body is producing more collagen and can ward off much of the damage. However, by the time you reach your mid-30s a build-up of sun damage, environmental oxidative stress, hormonal changes, and the accumulation of AGEs begins to take its toll at the same time your ability to repair the damage declines … making your skin look… well, old."

While glycation can't be completely stopped (after all, we can't stop eating), there are a number of pharmaceutical and cosmetic companies that have been working on "glycation busters" that have the ability to break the glycation-related cross-linking that's already formed. One such "glycation buster" is a revolutionary new, topically applied compound called Theraglycan-3, from SanMedica International.

Three separate clinical trials were conducted to establish the efficacy of Theraglycan-3. In the studies, women used a Theraglycan-3 cream twice a day (a 2% day cream in the morning and a 4% concentrated night cream before bed). They applied the Theraglycan-3 cream to half their skin and a placebo cream to the other half for two months. The autofluorescence technology proved Theraglycan-3 significantly reduced AGEs in the skin equal to an 8–10 year age differential compared to the placebo side. But what's more, because of the way AGEs occur, Theraglycan-3 can actually reduce their occurrence by blocking surface glycotoxin formation, helping to shield the skin from future glyco-damage, as well.

Why is this important? This is the first time an anti-glycation compound has been tested to reduce actual AGE content in human skin and make it appear measurably younger... 8–10 years younger, to be exact. This new glycation-busting formula is in the top-secret product SanMedica revealed at its Scientific Summit this past weekend, and will be sold under the trade name GlyTerra-gL. GlyTerra-gL and its unique Theraglycan-3 compound have been proven to decrease the age-related effects of sugar damage, reduce the look of fine lines, deep wrinkles and crow's feet, improve the appearance of age spots, loose, droopy, flaccid skin.