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The Next Generation of Peptides
By: Lydia Sarfati
Posted: November 24, 2009, from the December 2009 issue of Skin Inc. magazine.
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Botulinum toxin A is a purified form of botulism, a disease that can paralyze muscles. It works by attacking SNAP-25, a protein that is essential for the release of acetylcholine, the neurotransmitter responsible for triggering muscle contractions. Thus, the SNARE complex cannot assemble, the nerve signal cannot be transmitted, and the muscle cannot contract. Botulinum toxin A has the potential to result in inappropriate facial expression for weeks after the treatment, such as drooping eyelids or an uneven smile. Although these are temporary effects, there can be more serious risks involved. The FDA recently issued an order that Botox* and Dysport**, another neurotoxin inhibitor, must carry a warning label explaining that the agent may spread to sites other than the points of injection, which can result in difficulty breathing or swallowing.1
Where botulinum toxin A is limited to certain areas of the face, acetyl hexapeptide-3 can be applied anywhere without the invasion of injection and risk of migration, with a similar efficiency. A clinical study has concluded that an emulsion containing 10% acetyl hexapeptide-3 showed a average 30% reduction in the depth of wrinkles after 30 days of use.2
This indicates that there are ingredients that are noninvasive, safe and effective topical solutions for fine lines and wrinkles that may provide the smoothing effect you and your clients desire.
Smarter skin care
The future of skin care is leaning toward a more sophisticated and scientific approach. Products are emerging that can gently and effectively target, treat and even help prevent specific skin conditions. Why? Because skin care is smarter than it’s ever been. The skin care industry is examining the molecular processes of the skin and utilizing evolving technologies accordingly
Ingredients are being found that mimic the skin’s natural processes. Who would have ever thought that seaweed could smooth crow’s-feet or tea could soothe a sunburn? With biotechnology and peptide technology, skin care has only just begun to move forward. The possibilities are endless.