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Low-dose Green Tea Extract May Fight UV Damage

Posted: October 22, 2008

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The researchers did note however, that the green tea extract did not appear to affect the formation of thymidine dimers--DNA lesions most commonly caused by UV radiation. When lesions such as these go unrepaired they can lead to the formation of skin cancer, and it is the tumor-suppressor protein p53 that is often involved in the repair process.

Anti-inflammatory action

,p>If the green tea extract was working as a sunscreen, one would expect the number of UV-induced lesions to decrease. As this is not the case, the researchers concluded that the protective effect (as illustrated by the smaller number of p53 positive keratinocytes) must be linked to other green tea extract-mediated effects. Such effects are likely to include the extract’s anti-inflammatory properties and its ability to reduce oxidative damage.

 

The scientists believe they have shown green tea extract to reduce UVB-induced damage at cosmetically usable concentrations, suggesting the extract has potential as an everyday photochemopreventative agent.

Source: Experimental Dermatology, 2008, "Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls," Christian D. Mnich, Keith S. Hoek, Leila V. Virkki, Arpad Farkas, Christa Dudli, Elisabeth Laine, Mirjana Urosevic, Reinhard Dummer.