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Anti-aging Ingredient Possibly Linked to Tumor Development

Posted: March 13, 2008

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At present the data is not sufficient to come to any concrete conclusions--the ability to prevent tumors by AQP3 deletion does not prove a link between the proteins' upregulation and skin tumor formation.

However, according Verkman, it is 'not unreasonable' to suggest a link, and he advises caution in the use of such cosmetics. "Given the relationship between epidermal AQP3 expression and tumor cell proliferation, caution seems warranted in the use of cosmetics containing ingredients that increase epidermal AQP3 expression," he concludes.

Furthermore, he proposes that further studies are needed to investigate the relationship between the use of such cosmetics and the incidence of skin cancers., March 13, 2008