Treatment-induced Appearance Changes

• Follicular eruption or acnelike rash

• The skin around the fingernails and toenails is dry, cracked and peeling; the cuticle may swell; and ingrown nails, nail shedding and dark lines through the nails may occur

• Ingrown hair follicles

• Excessive dry skin with itchiness and irritation

• Dry peeling skin on palms and the soles of the feet, also known as hand-foot syndrome, which may be accompanied by tingling, pain and swelling

• Hair changes including thinning, loss, and change in color or texture

• Increased growth of eyelashes and eyebrows

• Hyperpigmentation, which may be generalized or focused on nail beds, mouth, tongue, palms and soles of the feet, and along the veins

• Telangiectasia or an eruption of tiny veins just below the skin surface