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AADA Updates Position on Isotretinoin
Posted: November 30, 2010
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Compliance should still be maintained with the manufacturer-sponsored and FDA-approved risk management program for prescribing isotretinoin (iPLEDGE). The AADA opposes on-line Internet dispensing, sharing, or use without physician supervision, because these activities do not provide for sufficient patient education about isotretinoin risks and do not require participation in the iPLEDGE program.
The position statement concludes that the prescription of isotretinoin for severe nodular acne continues to be appropriate as long as prescribing physicians are aware of the issues related to isotretinoin use.
“Physicians should to be alert to potential concerns, including IBD or psychiatric disturbance, educate their patients about these and other potential risks, and monitor their patients for any indication of these symptoms,” said Dr. James.
The updated position statement is based on review of the latest evidence regarding isotretinoin and the treatment of severe acne. “The effectiveness of isotretinoin therapy in the treatment of acne has been demonstrated in numerous clinical studies which are referenced in the position statement,” said Stephen P. Stone, MD, FAAD, chair of the AADA’s retinoids task force. “When and if new data become available, additional updates to the position statement will be considered.”