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A coffee habit, coupled with regular exercise, may help prevent skin cancers better than either factor alone, new research suggests.
The study was done only with animals, however, and it's not a reason to abandon standard sun-protection habits.
"You should not give up the sunblock," said Dr. Allan H. Conney, senior author of the study, published in this week's Proceedings of the National Academy of Sciences.
The findings aren't entirely new. "In earlier studies, we found caffeine and exercise -- either one by themselves -- inhibited ultraviolet light-induced skin cancer in mice," said Conney, the director of the Laboratory for Cancer Research at the School of Pharmacy at Rutgers, the State University of New Jersey.
But the new research shows that "the combination [of the two] works better," he said, providing a dramatically better anti-cancer result.
Both caffeine and exercise seem to help kill the UVB-damaged cells before malignancy sets in. "We really don't know how that happens," Conney said.
In the study, his team looked at four groups of hairless mice. The rodents' exposed skin is very vulnerable to the sun.
One group was given caffeinated water to drink each day, the equivalent of a person drinking a couple of cups of coffee a day, Conney said. Another group ran voluntarily on a running wheel, the equivalent of a person running two or two and a half miles every day, he said. (These mice will happily go on an exercise wheel if one is available, Conney said.) A third group had both the caffeine and the exercise, while a fourth group had neither and served as the control group.
The mice in all four groups were exposed to lamps that generated UVB radiation that damaged the skin cells' DNA.
While some degree of healthy, programmed skin cell death ("apoptosis") was seen in all four groups of mice, the caffeine drinkers and exercisers were best at killing off the damaged cells, the researchers found.
To find out how different the four groups were in terms of killing off damaged skin cells, the researchers looked at physical changes in those cells. They also looked at chemical markers, such as enzymes, involved in killing damaged cells.
The differences were dramatic. The caffeine drinkers showed a 96 percent increase in damaged cell death compared to the control group and the exercisers showed a 120 percent increase. Even more significant, the mice that drank caffeine and ran on the training wheel had a nearly 400 percent increase in cell death of damaged cells.
Whether this combination would work in people is not known, Conney said, although some research has found that caffeine and exercise does reduce certain cancer risks. He said he would like to do a clinical study in humans next.
More than a million non-melanoma skin cancers are diagnosed in the United States annually, according to the American Cancer Society. About 62,190 cases of melanoma, the most deadly skin cancer type, will be diagnosed this year.
A spokesman for the Skin Cancer Foundation urged caution in interpreting the study findings, however. "It will take years of extensive testing to determine whether this will be a worthwhile concept before you can say anything specific about it," said Dr. Michael Gold, founder of the Gold Skin Care Center in Nashville, Tenn.
"Mice and humans are very different. That said, we do know that caffeine applied topically has been popular as a 'cosmeceutical' anti-aging ingredient and might be useful in helping prevent non-melanoma skin cancers," Gold said. "The concept of systemic caffeine needs to be addressed further. We also know that moderate exercise is an immune moderator and can help ward off cancers and other diseases."
He echoed standard advice to wear sunscreen when out in the sun. "If you are exercising outside you must wear sunscreen no matter what," Gold said. "If you don't protect yourself from the sun while exercising outdoors you are increasing your risk of getting non-melanoma skin cancers and melanoma. Protecting yourself from the sun is currently the only proven way to prevent skin cancer."
By Kathleen Doheny, HealthDay News, July 30, 2007
Sawgrass Marriott Resort & Spa in Ponte Verda Beach, FL, is offering a relaxing spa package called Green Envy to coincide with the golfing season. While men experience the nearby famed golf course, women can receive spa treatments, including the Aroma Body Glow and European Cleansing Facial. 800-457-4653
Belvedere USA Corporation announced that it is now a privately held company after completion of a purchase agreement between two senior company managers and parent company Proctor & Gamble. Horst Ackermann was president of Belvedere USA and Barry Sanders served as vice president of finance and administration for the company when it was a subsidiary of P&G. Their new titles are principal/chief operating officer and principal/president, respectively.
Belvedere is a leading North American manufacturer and marketer of salon and spa furnishings and equipment. The company dates from 1927 and has always been based in Belvidere, Ill.
The structure of the company will not change under the new ownership.
By Cathy Christensen
From cooling devices to ceiling-hung TVs, spas are making hair removal a better encounter every day.
Donating an entire day to an eyebrow “wax-a-thon” and raffling off facials, massages and products, the spa Face, Body & Soul in Simi Valley, CA, recently held a fundraiser for the Los Angeles County University of Southern California Hospital. Clients received eyebrow waxes in exchange for bringing in men’s clothing items or cash donations which, like the raffle proceeds, were given to the hospital to help clothe homeless men seeking medical attention at the county facility. 805-584-5000
Practiced by millions of individuals to reduce stress and anxiety, improve concentration, and even lower blood pressure, meditation is among the most commonly used alternative therapies in the world. Earlier today, at the Alzheimer’s Association International Conference on the Prevention of Dementia in Washington, D.C., results from a University of Pennsylvania study were unveiled confirming for the first time that daily practice of meditation can improve cognitive function among individuals with memory complaints.
Researchers began their investigation by conducting a series of neurological and memory tests on each subject, who ranged in age from 52-70, with either a history of memory complaints or a diagnosis of mild cognitive impairment. Single Photon Emission Computed Tomography (SPECT) scans, a brain imaging technique which measures cerebral blood flow, were also conducted on each subject. Following the initial tests, subjects were taught the techniques of Kirtan Kriya, the most widely practiced meditation in the Kundalini Yoga tradition, and instructed to practice a 12-minute meditation each day for eight weeks.
While follow up testing confirmed statistically significant improvements in memory among all of the study's subjects, the most significant outcome of the study was the stark contrast between the pre and post-training SPECT scans. Follow up scans showed dramatic increases in blood flow to the posterior cingulate gyrus, the region of the brain associated with learning and memory. It is the first region of the brain to decline in individuals diagnosed with Alzheimer’s disease, which helps to explain why the blood flow-producing meditation has such a profound impact on cognitive functioning.
“This exciting study confirms what we have been observing in clinical practice for many years, that meditation is one of the most effective tools to address memory loss,” said Dharma Singh Khalsa, M.D., president and medical director of the Alzheimer’s Research and Prevention Foundation, the non-profit organization which sponsored the study. “While we are planning additional research in this area, we can say today with confidence that daily meditation is recommended as part of an integrated brain longevity strategy to delay, even prevent, cognitive decline,” he continued.
Andrew Newberg, M.D., assistant professor of radiology at the University of Pennsylvania School of Medicine, and the study’s principal investigator, concurred. “For the first time, we are seeing scientific evidence that meditation enables the brain to actually strengthen itself, and battle the processes working to weaken it,” said Newberg. “If this kind of meditation is helping patients with memory loss,” he continued, “we are encouraged by the prospects that daily practice may even prevent neurodegenerative diseases such as Alzheimer’s.”
For more information, please visit the Alzheimer’s Research and Prevention Foundation at www.alzheimersprevention.org.
The SháNah Spa and Wellness Center located in the Bishop’s Lodge Ranch Resort & Spa is offering Watsu massage, a combination of water and shiatsu therapy. One of a handful of American spas offering the treatment, the spa uses the procedure to help with total relaxation of the spinal column. 800-732-2240
Yoga's postures, controlled breathing and meditation may work together to help ease brains plagued by anxiety or depression, a new study shows.
Brain scans of yoga practitioners showed a healthy boost in levels of the neurotransmitter gamma-aminobutyric (GABA) immediately after a one-hour yoga session. Low brain levels of GABA are associated with anxiety and depression, the researchers said.
"I am quite sure that this is the first study that's shown that there's a real, measurable change in a major neurotransmitter with a behavioral intervention such as yoga," said lead researcher Dr. Chris Streeter, assistant professor of psychiatry and neurology at the Boston University School of Medicine.
She believes yoga could prove a useful tool to help people battling depression and anxiety disorders. "We're not advocating that they chuck their medication, but I would advise that they could use it as an adjunct and see how they are doing," Streeter said.
Her team published its findings in the May issue of the Journal of Alternative and Complementary Medicine.
In the study, the Boston researchers used high-tech magnetic resonance spectroscopic imaging to gauge levels of GABA in the brains of eight long-time yoga practitioners and 11 non-practitioners. The participants were healthy, and none was diagnosed with a major psychiatric condition.
Brain scans were taken before the beginning of the experiment. Then, the yoga group was asked to engage in the meditative practice for 60 minutes, while the non-yoga group simply read. The researchers then re-scanned each participant's brain, looking specifically at GABA levels.
"We showed a 27 percent increase in the brain GABA levels of those doing yoga -- a really significant increase," Streeter said. No such change was noted in the non-practitioners who had just read.
She said the style or school of yoga practiced didn't seem to matter. "We had hatha, ashtanga, bikram, vinyasa, and kripalu" practitioners included in the yoga group, Streeter said, "and many had been trained in several different schools."
According to Streeter, "this all gives us one of the mechanisms by which yoga may be having a beneficial effect. There could be other mechanisms."
But another expert pointed to what he considered flaws in the research.
Zindel Segal, chairman of psychotherapy and a professor of psychology and psychiatry at the University of Toronto, has for years studied the use of behavioral interventions to alleviate psychological woes.
He said the Boston researchers were to be commended for using brain scan imaging technologies to investigate the effectiveness of these techniques. But he questioned why the yoga group was simply compared to a sedentary reading group and not to another movement-based group.
"Exercise itself may have some effects on GABA, so I think in this study, you'd really want that comparison," he said. Including such a control group would make it clear that it was yoga and not just an hour of physical exertion that was responsible for the brain changes.
He also pointed out that all of the people in the study were mentally healthy, and clinical depression and anxiety disorders involve more than the "daily fluctuations in stress and tension" that healthy individuals are prone to.
"We know that yoga can have a profound effect" on smoothing out life's daily ups and downs, Segal said. "But so does working out on a Stairmaster for an hour."
Segal also questioned the role of GABA in depression. While it may play a role in anxiety disorders, "GABA is not one of the main neurotransmitters that seems to be a part of the depression story," he said. Other neurochemicals -- most notably serotonin -- play much bigger roles in the disorder, he said.
None of this means that the study's findings are without merit, Segal said. "In fact," he said, "we have a program called 'mindfulness-based cognitive therapy,' where we do use yoga, as well as mindfulness meditation," as therapeutic tools. Streeter's findings "suggest the need for more study of these practices," he said.
Streeter agreed that her study is probably just a beginning.
"I think what's important about this study is that it shows that by using really cutting-edge neuroimaging technology, we can measure real changes in the brain with behavioral interventions -- changes that are similar to those that we see with pharmacologic treatments," she said.
Would other mind-body practices -- Tai Chi, for example -- produce similar effects?
"I think that's very possible," Streeter said. "I suspect that all roads lead up the mountain."
HealthDay News, Thursday, June 7, 2007 By E. J. Mundell
The percentage of American adults who got sunburned increased from 31.8 percent to 33.7 percent from 1999 and 2004, a sign that many people aren't using proper sun protection, a new study found.
The study also found that significant portions of most racial and ethnic groups reported getting sunburned in the three years -- 1999, 2003, and 2004 -- when the data was collected through surveys.
The study authors noted that sunburn increases the risk of developing melanoma and basal cell carcinoma skin cancers.
Sunburn rates in 2004 were 46.9 percent for non-Hispanic white men; 39.6 percent for non-Hispanic white women; 12.4 percent for Hispanic black men; 9.5 percent for Hispanic black women; 16.2 percent for male Asians/Pacific Islanders; 16.1 percent for female Asians/Pacific Islanders; 30.4 percent for male American Indians/Alaska Natives; 21.5 percent for female American Indians/Alaska Natives; and 5.8 percent for male and female non-Hispanic blacks.
Overall, men were more likely to get sunburned (35.8 percent in 1999, 37 percent in both 2003 and 2004) than women (28 percent, 30.2 percent and 30.3 percent, respectively).
The highest rate of sunburn prevalence among whites in any of the three years was in Utah (51.3 percent in 2003), while the lowest was in Arizona (25.7 percent in 1999). Twenty states reported a statistically significant increase in sunburn rates among whites, while four states -- Indiana, Iowa, Kentucky and Louisiana -- reported a significant decrease.
The study findings are published in Friday's edition of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
Sunburn can be prevented by following such sun-protection measures as wearing a hat; covering up while in the sun; avoiding the sun between 10 a.m. and 4 p.m.; and using sunscreen with a sun protection factor (SPF) of 15 or higher.
HealthDay News, May 31, 2007
By Alphonse Wiebelt
Makeup tips and application methods to make a bride beautiful on her big day.