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Omega-6 Fatty Acid Critical to Skin Health

Posted: May 12, 2010

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"We usually think of inflammation as a bad thing, but in this case, prostaglandins prevented dermatitis, which is an inflammatory reaction. We measured prostaglandin levels in the animals' skin, and when we fed arachidonic acid to the knockout mice, they resumed making these important chemical compounds," he said.

Nakamura cautioned that there are still things they don't understand about the function of this omega-6 fatty acid. "This new knowledge is a starting point in understanding the mechanisms that are involved, and we need to do more research at the cellular level."

The study was published in a recent issue of the Journal of Lipid Research. Co-authors are Chad K. Stroud, Takayuki Y. Nara, Manuel Roqueta-Rivera, Emily C. Radlowski, Byung H. Cho, Mariangela Segre, Rex A. Hess, and Wanda M. Haschek, all of the U of I, and Peter Lawrence, Ying Zhang, and J. Thomas Brenna of Cornell University. Funding was provided in part by a USDA National Needs Fellowship Award and a grant from the National Institutes of Health.

From ScienceDaily.com, April 14, 2010