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Immune System Dysfunction Pinpointed in Melanoma Cases
Posted: May 15, 2007
page 2 of 2"Doctors knew it worked in some people but didn't know why," Lee said in a prepared statement. This study suggests that prolonged interferon treatment may work by overcoming the immune system's inability to respond to interferon.
Previous research has found that cancer patients often have immune system problems, but, until now, scientists didn't know which genes or pathways were at the root of the trouble. Identification of this interferon response disruption may boost efforts to develop vaccines for different types of cancer, the Stanford researchers said.
"We think this is a dominant way that immune dysfunction occurs in people with cancer," Lee said
HealthDay News, May 14, 2007