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Extra Wrinkles a Bad Sign for Smokers

Posted: June 14, 2006

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In the study, the team wanted to see if genetic factors that predispose smokers to COPD might also predispose them to wrinkles.

The researchers, based at Royal Devon and Exeter NHS Foundation Trust, analyzed data on 149 current and former middle-aged smokers, 68 of whom (45.6 percent) had COPD. The participants came from 78 families.

Eighty-three percent had no facial wrinkling or only minor lines, but close to 17 percent had considerable wrinkling.

Lung strength and function, measured in all participants, turned out to be significantly lower in those with extensive wrinkling than in those with smoother faces.

People with heavy wrinkles were also five times more likely to have COPD than those without wrinkles. People with facial wrinkling also had triple the risk of suffering from more severe emphysema.