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University Reports Retinol Reduces Wrinkles

Posted: June 14, 2007

The University of Michigan Medical School recently reported that retinol reduces the fine lines and wrinkles associated with natural aging. The report was published in the May issue of the Archives of Dermatology.

According to the university report, retinol, or vitamin A, is proven to aid fine lines and wrinkles in addition to its known benefit of repairing skin damage. To test the efficacy of retinol, the researchers applied 0.4% retinol lotion to the upper, inner arm of 36 subjects. A control lotion was applied to the subject's other arm. These lotions were applied three times a week for 24 months.

The researchers reported that the wrinkles started to lessen after four weeks of treatment with retinol. The reason reportedly was an induced increase in the expression of glycosaminoglycans (GAGs) in skin and the increase of collagen production.